Publications

  • Magnúsdóttir, Elín Ingibjörg; Grujic, Mirjana; Bergman, Jessica; Pejler, Gunnar et al.

    Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1

    Part of Journal of Neuroinflammation, 2020.

    Open access
  • Ma, Haisha; Gao, Tianle; Jakobsson, Jon E. T.; Weman, Hannah M. et al.

    The Neuropeptide Y Y-2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y-2 Activation Reduces Histaminergic and IL-31-Induced Itch

    Part of Journal of Pharmacology and Experimental Therapeutics, p. 73-82, 2020.

    Open access
  • Freitag, Fabio Batista; Ahemaiti, Aikeremu; Jakobsson, Jon E. T.; Weman, Hannah M. et al.

    Spinal gastrin releasing peptide receptor expressing interneurons are controlled by local phasic and tonic inhibition

    Part of Scientific Reports, 2019.

    Open access
  • Jakobsson, Jon E. T.; Ma, Haisha; Lagerström, Malin C.

    Neuropeptide Y in itch regulation

    Part of Neuropeptides, 2019.

    Open access
  • Magnúsdóttir, Elín Ingibjörg; Grujic, Mirjana; Roers, Axel; Hartmann, Karin et al.

    Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin

    Part of Molecular Pain, 2018.

    Open access
  • Gao, Tianle; Ma, Haisha; Xu, Bo; Bergman, Jessica et al.

    The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch

    Part of Journal of Investigative Dermatology, p. 2405-2411, 2018.

    Open access
  • Spencer, Nick J.; Hibberd, Tim J.; Lagerström, Malin; Otsuka, Yoichiro et al.

    Visceral pain: Novel approaches for optogenetic control of spinal afferents

    Part of Brain Research, p. 159-164, 2018.

  • Haring, Martin; Zeisel, Amit; Hochgerner, Hannah; Rinwa, Puneet et al.

    Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

    Part of Nature Neuroscience, p. 869-880, 2018.

  • Spencer, Nick J.; Magnúsdóttir, Elín Ingibjörg; Jakobsson, Jon E. T.; Kestell, Garreth et al.

    CGRP alpha within the Trpv1-Cre population contributes to visceral nociception

    Part of American Journal of Physiology - Gastrointestinal and Liver Physiology, p. G188-G200, 2018.

  • Aresh, Bejan; Freitag, Fabio B.; Perry, Sharn; Blümel, Edda et al.

    Spinal Cord Interneurons Expressing the Gastrin-Releasing Peptide Receptor Convey Itch Through VGLUT2-Mediated Signaling

    Part of Pain, p. 945-961, 2017.

    Open access
  • Viereckel, Thomas; Dumas, Sylvie; Smith-Anttila, Casey J. A.; Vlcek, Bianca et al.

    Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson's Disease

    Part of Scientific Reports, 2016.

    Open access
  • Rogoz, Katarzyna; Aresh, Bejan; Freitag, Fabio Batista; Pettersson, Hanna et al.

    Identification of a Neuronal Receptor Controlling Anaphylaxis

    Part of Cell reports, p. 370-379, 2016.

    Open access
  • Rogóz, Katarzyna; Stjarne, Ludvig; Kullander, Klas; Lagerström, Malin C.

    VGLUT2 controls heat and punctuate hyperalgesia associated with nerve injury via TRPV1-Cre primary afferents

    Part of PLoS ONE, 2015.

    Open access
  • Rogóz, Katarzyna; Andersen, Helena H.; Lagerström, Malin C.; Kullander, Klas

    Multimodal Use of Calcitonin Gene-Related Peptide and Substance P in Itch and Acute Pain Uncovered by the Elimination of Vesicular Glutamate Transporter 2 from Transient Receptor Potential Cation Channel Subfamily V Member 1 Neurons

    Part of Journal of Neuroscience, p. 14055-14068, 2014.

  • Caruso, Vanni; Lagerström, Malin C.; Olszewski, Pawel K.; Fredriksson, Robert et al.

    Synaptic changes induced by melanocortin signalling

    Part of Nature Reviews Neuroscience, p. 98-110, 2014.

  • Rogoz, Katarzyna; Andersen, Helena Haddadi; Kullander, Klas; Lagerström, Malin C.

    Glutamate, Substance P, and Calcitonin Gene-Related Peptide Cooperate in Inflammation-Induced Heat Hyperalgesia

    Part of Molecular Pharmacology, p. 322-334, 2014.

  • Rogoz, Katarzyna; Lagerström, Malin C.; Dufour, Sylvie; Kullander, Klas

    VGLUT2-dependent glutamatergic transmission in primary afferents is required for intact nociception in both acute and persistent pain modalities

    Part of Pain, p. 1525-1536, 2012.

  • Lagerström, Malin C.; Rogoz, Katarzyna; Abrahamsen, Bjarke; Lind, Anne-Li et al.

    A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain

    Part of Proceedings of the National Academy of Sciences of the United States of America, p. 5789-5794, 2011.

  • Zhao, Jing; Yuan, Guanglu; Cendan, Cruz M.; Nassar, Mohammed A. et al.

    Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain

    Part of Molecular Pain, p. 77-, 2010.

  • Lagerström, Malin C.; Rogoz, Katarzyna; Abrahamsen, Bjarke; Persson, Emma et al.

    VGLUT2-Dependent Sensory Neurons in the TRPV1 Population Regulate Pain and Itch

    Part of Neuron, p. 529-542, 2010.

  • Nordström, Karl J V; Lagerström, Malin C; Wallér, Linn M J; Fredriksson, Robert et al.

    The Secretin GPCRs descended from the family of Adhesion GPCRs

    Part of Molecular biology and evolution, p. 71-84, 2009.

  • Wallén-Mackenzie, Åsa; Nordenankar, Karin; Fejgin, Kim; Lagerström, Malin C et al.

    Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

    Part of Journal of Neuroscience, p. 2238-2251, 2009.

  • Lagerström, Malin C.; Schiöth, Helgi B.

    Structural diversity of G protein-coupled receptors and significance for drug discovery

    Part of Nature reviews. Drug discovery, p. 339-357, 2008.

  • Pickering, Chris; Hägglund, Maria; Szmydynger-Chodobska, Joanna; Marques, Fernanda et al.

    The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

    Part of BMC neuroscience (Online), p. 97-, 2008.

  • Lagerström, Malin C.; Rabe, Nadine; Haitina, Tatjana; Kalnina, Ineta et al.

    The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

    Part of Journal of Neurochemistry, p. 1129-1142, 2007.

  • Gezelius, Henrik; Wallén-Mackenzie, Åsa; Enjin, Anders; Lagerström, Malin et al.

    Role of glutamate in locomotor rhythm generating neuronal circuitry

    Part of Journal of Physiology - Paris, p. 297-303, 2006.

  • Lagerström, Malin C.; Hellström, Anders R.; Gloriam, David E.; Larsson, Thomas P. et al.

    The G protein-coupled receptor subset of the chicken genome

    Part of PloS Computational Biology, p. e54-, 2006.

  • Lagerström, Malin C.; Fredriksson, Robert; Bjarnadottir, Thora; Fridmanis, Davids et al.

    Origin of the prolactin-releasing hormone (PRLH) receptors: Evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution

    Part of Genomics, p. 688-703, 2005.

  • Bjarnadóttir, Thóra K.; Fredriksson, Robert; Höglund, Pär J.; Gloriam, David E. et al.

    The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

    Part of Genomics, p. 23-33, 2004.

  • Haitina, Tatjana; Klovins, Janis; Andersson, Jan; Fredriksson, Robert et al.

    Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

    Part of Biochemical Journal, p. 475-486, 2004.

  • Fredriksson, Robert; Gloriam, David; Höglund, Pär; Lagerström, Malin et al.

    There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini

    Part of Biochemical and Biophysical Research Communications - BBRC, p. 752-734, 2003.

  • Lagerström, Malin C.; Klovins, Janis; Fredriksson, Robert; Fridmanis, Davids et al.

    High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3

    Part of Journal of Biological Chemistry, p. 51521-51526, 2003.

  • Fredriksson, Robert; Lagerström, Malin C.; Lundin, Lars-Gustav; Schiöth, Helgi B.

    The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families: Phylogenetic Analysis, Paralogon Groups, and Fingerprints

    Part of Molecular Pharmacology, p. 1256-1272, 2003.

  • Lagerström, Malin C.; Hellström, Anders R.; Larsson, Thomas P.; Schiöth, Helgi B. et al.

    The chicken G protein-coupled receptor (GPCR)-ome